Family with Sequence Similarity 120A (FAM120A) (Middle Region) Peptide
FAM120A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976594
Quick Overview for Family with Sequence Similarity 120A (FAM120A) (Middle Region) Peptide (ABIN976594)
Target
FAM120A
(Family with Sequence Similarity 120A (FAM120A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-FAM120A antibody (Catalog #: ARP55089_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FAM120A (Family with Sequence Similarity 120A (FAM120A))
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Background
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FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Alias Symbols: C9orf10, DNAPTP1, DNAPTP5, MGC111527, MGC133257, OSSA
Protein Size: 1118 -
Molecular Weight
- 122 kDa
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Gene ID
- 23196
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NCBI Accession
- NM_014612, NP_055427
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UniProt
- Q9NZB2
Target
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